Cystatin C With Glomerular Filtration Rate, Estimated (eGFR) LabCorp

$62.00

LabCorp Test #: 121265; CPT: 82610

Disclaimer: Due to state regulations, Defy Medical does not offer on-demand lab testing in New York, New Jersey, Pennsylvania, Rhode Island, or Massachusetts.

Since it is formed at a constant rate and freely filtered by the healthy kidney, cystatin C is a good marker of renal function. Serum concentrations of cystatin C are almost totally dependent on glomerular filtration rate (GFR). A reduction in GFR causes a rise in the concentration of cystatin C.1,2

Can be used as a confirmatory test for the diagnosis of chronic kidney disease (CKD) in patients with a decreased GFR as estimated from creatinine.

Data suggests that 3.6% of U.S. adults would be classified as having CKD solely on the basis of a creatinine-based GFR estimate of 45 to 59 mL per minute per 1.73m2. A strategy of measuring cystatin C when the creatinine-based estimate is in this range and then reestimating GFR with the use of both these markers could correctly reclassify a substantial proportion of such patients as not having CKD and not being at high risk.

Can also be used to screen for CKD among persons who have a creatinine-based GFR estimate of 60 to 74 mL per minute per 1.73m2 without albuminuria (10.9% of US adults) or to obtain a more accurate estimation of GFR in patients with muscle wasting or chronic illness.

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Why To Buy

This Cystatin C test from Defy Medical helps assess your kidney function, which can explain symptoms like fatigue, swelling, and shortness of breath, potentially identifying early kidney problems.

Finding the cause(s) of:

  • Fatigue: This test checks kidney function, as poor kidney health can lead to a buildup of waste products causing tiredness.
  • Kidney function decline: Cystatin C is a direct measure of how well your kidneys are filtering waste from your blood.
  • Loss of appetite: Declining kidney function can cause a buildup of toxins affecting appetite.
  • Nausea: Poor kidney function can lead to waste buildup causing nausea.
  • Shortness of breath: Kidney problems can lead to fluid buildup in the lungs causing breathing difficulties.
  • Swelling: Poor kidney function can cause fluid retention leading to swelling, especially in the legs and ankles.
Symptoms Fatigue, Kidney function decline, Loss of appetite, Nausea, Shortness of breath, Swelling